PPARG antibody (AA 1-477)

Catalog No. ABIN7163013

The Rabbit Polyclonal anti-PPARG antibody has been validated for IHC, ELISA and IF. It is suitable to detect PPARG in samples from Human.

Quick Overview for PPARG antibody (AA 1-477) (ABIN7163013)

Target: PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPARG antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-PPARG Antibody

Binding Specificity: AA 1-477

Purpose: PPARG Antibody

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Peroxisome proliferator-activated receptor gamma protein (1-477AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PPARG

Target: PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

Alternative Name: PPARG

Background:

Background: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses.

Aliases: CIMT1 antibody, GLM1 antibody, NR1C3 antibody, Nuclear receptor subfamily 1 group C member 3 antibody, OTTHUMP00000185032 antibody, OTTHUMP00000185036 antibody, Peroxisome proliferator activated nuclear receptor gamma variant 1 antibody, Peroxisome proliferator activated receptor gamma 1 antibody, Peroxisome Proliferator Activated Receptor gamma antibody, Peroxisome proliferator-activated receptor gamma antibody, PPAR gamma antibody, PPAR-gamma antibody, PPARG antibody, PPARG_HUMAN antibody, PPARG1 antibody, PPARG2 antibody, PPARgamma antibody

UniProt: P37231

Pathways: MAPK Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation